View each tab to see the adverse effects of plastic chemicals on health at
every stage of life.
Bisphenols
Consistent and significant evidence of harm
Strong reason for concern
Pregnancy and birth related Click on dots or health labels for details
Pregnant Female
Infant
Child
Adult Female
Adult Male
Phthalates
Consistent and significant evidence of harm
Strong reason for concern
Pregnancy and birth related Click on dots or health labels for details
Pregnant Female
Infant
Child
Adult Female
Adult Male
PCBs
Consistent and significant evidence of harm
Strong reason for concern
Pregnancy and birth related Click on dots or health labels for details
Pregnant Female
Infant
Child
Adult Female
Adult Male
PBDEs
Consistent and significant evidence of harm
Strong reason for concern
Pregnancy and birth related Click on dots or health labels for details
Pregnant Female
Infant
Child
Adult Female
Adult Male
PFAS
Consistent and significant evidence of harm
Strong reason for concern
Pregnancy and birth related Click on dots or health labels for details
Pregnant Female
Infant
Child
Adult Female
Adult Male
Systematic Reviews
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The methodology developed by JBI and Minderoo for the original
Umbrella Review was applied to evaluate systematic reviews
published up until August 2025. PlasticHealthAware presents the
findings from 196 systematic reviews
Within the included 6,841 identified meta-analyses, there were
multiple specific subgroup-analyses. This overview draws from a
systematically selected 3,631 meta-analyses, excluding for
example geographic, analytical method, and matrix subgroups.
The 195 Systematic reviews draw data from a combined 1,621
unique primary studies. Many more primary studies cover the
intersection between plastic chemical exposure and human
health outcomes.
There were 92 unique exposures identified in the included meta-analyses.
This includes individual chemicals, as well as combined exposures of multiple chemicals.